Description
Case studies are a useful way for you to apply your knowledge of pharmacokinetics and pharmacodynamic aspects of pharmacology to specific patient cases and health histories.
For this Assignment, you evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.
RESOURCES
Be sure to review the Learning Resources before completing this activity.
Click the weekly resources link to access the resources.
WEEKLY RESOURCES
To Prepare:
Review the case study posted in “Announcements” by your Instructor for this Assignment
Review the information provided and answer questions posed in the case study
When recommending a medication, write out a complete prescription for the medication
Whenever possible, use clinical practice guidelines in developing your answers when possible
Include at least three references to support your answer and cite them in APA format.
Case study
Pharmacodynamics and pharmacokinetics are the two branches of pharmacology. Remember, pharmacokinetics describes what the body does to the drug through absorption, distribution, metabolism, and excretion (ADME), whereas pharmacodynamics describes what the drug does to the body.
When selecting drugs and determining dosages for patients, it is essential to consider individual patient factors that might impact the patient’s pharmacokinetic and pharmacodynamic processes. These patient factors include genetics, gender, ethnicity, age, behavior (i.e., diet, nutrition, smoking, alcohol, illicit drug abuse), and/or pathophysiological changes due to disease.
ASSIGNMENT
Case studies are a useful way for you to apply your knowledge of pharmacokinetics and pharmacodynamic aspects of pharmacology to specific patient cases and health histories.
For your Week 2 assignment, evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.
To Prepare:
Review assignment rubric and case studies. Be sure to thoroughly answer ALL questions.
Explain the problem and discuss how you would address the problem.
When recommending medications, write out a complete prescription for each medication. What order would you send to a pharmacy? Include drug, dose, route, frequency, duration (if applicable), indication for use, quantity and # of refills.
An example prescription is as follows: lisinopril 10mg #30, take 1 tab PO once daily for high blood pressure, refills: 2.
Also state if you would continue, discontinue or taper the patient’s current medications.
Answer questions using your required learning resources, clinical practice guidelines, Medscape, etc.
Include at least three references to support each scenario and cite them in APA format. Please include in-text citations. You do not need an introduction or conclusion paragraph.
SCENARIO 1
Mark Johnson is a 72 year old male recently prescribed warfarin 5 mg daily for DVT treatment. His PMH includes hypertension, hyperlipidemia and osteoarthritis. He is currently on HCTZ 25 mg po daily, celecoxib 200 mg po daily, fluvastatin 40 mg po daily, and Goody’s Powder 1 packet as needed for pain. He has no known allergies. What changes in his medications would you make? What alternatives might you prescribe (include complete medication orders)? How would a CYP2C9 polymorphism affect drug therapy? How would you monitor therapy?
SCENARIO 2
Utilizing the pill identifier, enter the following characteristics to identify the medication. What medication and strength is identified? What is the first-pass effect and how does it affect drug therapy with this medication? What is bioavailability and what route is considered to have 100% bioavailability? How can this medication be given to counter the first pass effect?
Imprint (P 80) Shape (Round) Color (Yellow) Form (Tablet) Scoring (Single)
SCENARIO 3
Alex is a 52-year-old male following up on his labs that were drawn last week. He smokes 1 pack per day. He is currently on lisinopril 20 mg po daily, semaglutide (Ozempic) 0.5 mg SC qWeek, and St. John’s Wort. Fasting lipid profile shows total cholesterol 260, LDL cholesterol 160, HDL cholesterol 35, and Triglycerides 220. What treatment plan would you implement for Alex’s lipid profile? What is the goal Total Cholesterol (TC), HDL-C, LDL-C, and Triglyceride level for Alex? How would you monitor the effectiveness of your treatment plan? How many risk factors for coronary artery disease does this patient have? Identify them specifically.
SCENARIO 4
Sandra is a 55-year-old African American female that was prescribed Toprol XL 50 mg daily for high blood pressure. Her PMH consists of depression treated with venlafaxine 225 mg daily. She states that she only occasionally takes her little white pill because she does not like the side effects of fatigue and dizziness. Her blood pressure today is 158/92. What information would you provide to the patient at her visit? What is her goal blood pressure? How would you improve Sandra’s medication therapy (include a complete medication order)?